Medical device innovation
On-body drug delivery device with Covestro plastic
Biologics are injected or infused, which typically requires inconvenient visits to specialty healthcare facilities or painful self-injections for patients. To solve these challenges, Enable Injections, Inc. developed a disposable on-body drug delivery device.
Covestro supported Enable Injections every step of the way from material selection to in-house part testing and manufacturing support. The housing of the on-body device features Makrolon®Rx1805 polycarbonate in a purple tint. Bayblend® M850 XF polycarbonate/acrylonitrile butadiene styrene (PC+ABS) blend in a white tint is featured on the transfer system, which allows the patient to easily transfer the biologic drug from its original container to the Enable on-body delivery device.
- Highly transparent and easily processed by injection molding.
- Extremely well-suited for medical technology applications that require contact with body fluids and infusion liquids.
- Good chemical resistance and high degree of dimensional stability.
- This polycarbonate grade can be sterilized with high energy beams, contributing to patient safety.
Just what the doctor ordered
Chemical-resistant, flame-retardant polycarbonate for medical devices
Merz, a global aesthetics and neurotoxin company headquartered in Frankfurt, Germany, needed polycarbonate materials for components of its Cellfina® System. The Cellfina® System is the only FDA-cleared, minimally invasive procedure shown to improve the appearance of cellulite for up to three years.
The motor module of the Cellfina® System is disinfected between uses with aggressive disinfectant wipes and required a high-quality proven material to meet a variety of requirements including chemical resistance and flame redardance.
Covestro worked closely with Merz, providing chemical data, test plaques and custom color matching. Merz selected Makroblend® M4000 FR polycarbonate/polybutylene terephthalate (PC+PBT) blend for the housing of the motor module of its Cellfina® System. The device also features Makrolon® 2458 polycarbonate in the sterilized disposable parts used with the system. Both materialsare durable enough to protect the device’s electronic components, yet are still aesthetically pleasing.
- Lightweight Makrolon® 2458 polycarbonate has easy-release properties and low viscosity for ease of processing.
- Makroblend® M4000 FR PC+PBT blend provides flame retardancy of V-0 at 2.0 mm and 5VA at 3.0 mm, a key attribute for an electromechanical device.
- The selected Makroblend® grade offers superior chemical resistance against disinfectant wipes.
- Makroblend® M4000 FR PC+PBT blend delivers high toughness and reduced susceptibility to stress cracking.
Easier, comfortable diabetic treatment
Needle-free injections made possible with polycarbonate
To meet the needs of a growing number of diabetes patients, QS Medical Technology Co., Ltd. (QS) developed a new needle-free injection technology. These high-quality injectors make life easier and more comfortable for millions of patients in China and around the world.
The needle-free injector’s plastic drug-delivery components and ampoule bottle require a material that can achieve strength, toughness, precision molding stability and radiation sterilization resistance.
Featuring durability, processability and design flexibility, Makrolon® Rx1805 polycarbonate from Covestro met QS’ needs for producing the insulin-delivery interface and molding the medication ampoules. This medical-grade polycarbonate ensures that the drug-delivery component can consistently puncture through the plug of an insulin ampoule. It also allows for the drug-sampling needle and the protective cover of the drug suction apparatus to be injection molded in one shot.
- Makrolon® Rx1805 polycarbonate is biocompatible according to ISO 10993-1 test requirements, meaning it is tested for human contact.
- This grade of polycarbonate offers excellent impact resistance.
- Featuring a high lipid resistance, Makrolon® Rx1805 polycarbonate is not easily damaged by lipids.
- This medical-grade polycarbonate is acceptable for sterilization, or disinfection, with high-energy radiation.
- Makrolon® Rx1805 polycarbonate offers accuracy in molding size and remains stable under different application environments.
Bio-compatible, Lightweight Polycarbonate Utilized in Respiratory Device
The Breathe Non-Invasive Open Ventilation (NIOV) System technology is a better solution. By reducing the overall size of the ventilation system, it supports patient mobility and independence.
Makrolon® polycarbonate from Covestro helps Breathe Technologies Inc. achieve the high-performing yet portable device design. The Breathe NIOV System is a one-pound, non-invasive mechanical ventilator that can be used in home and institutional settings. Breathe Technologies explains that the device utilizes novel venturi principle technology in a comfortable facial interface that can be worn while talking and exercising.
The patient interface and air/oxygen path components utilize injection-molded Makrolon® 2858. This grade is suitable for ETO and steam sterilization at 121 °C and is biocompatible according to many ISO 10993-1 test requirements, making it an ideal choice for medical devices. Makrolon® 2858 also features easy release and medium viscosity and is available in transparent and opaque colors. The device components made of Makrolon® are intricate in design and require optimal functionality for patient safety.
The Breathe NIOV System has received five 510(K) clearances from the U.S. FDA for use with compressed oxygen or compressed air for home and institutional use, and includes invasive and noninvasive circuits.
- Medium viscosity
- Easy release
- Medical device grade
- Available in transparent and opaque colors
- Suitable for ETO and steam sterilization at 121 °C; biocompatible according to many ISO 10993-1 test requirements